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Quantitative diagnostics

Organ function,
measured, not guessed.

Six validated indices and a physiologic stage from a single non-invasive scan. Better information leads to better decisions sooner, and without a biopsy.

How it works
See the evidence
PHM · Perfused Hepatic MassfLV · Functional Liver VolumefSV · Functional Spleen VolumeHAI · Hepatic Activity IndexeFS · Estimated Fibrosis StageeEV · Estimated Esophageal VaricesH0–H5 Physiologic StagingAnchored by the HALT-C trialPHM · Perfused Hepatic MassfLV · Functional Liver VolumefSV · Functional Spleen VolumeHAI · Hepatic Activity IndexeFS · Estimated Fibrosis StageeEV · Estimated Esophageal VaricesH0–H5 Physiologic StagingAnchored by the HALT-C trial

Diagnostic indices from one scan

Peer-reviewed publications

Year prospective multi-center trial

Physiologic stages (H0–H5)

The problem

Fibrosis tells you what happened. PROMEDX tells you what happens next.

Blood panels and elastography are estimates of scarring. Our platform directly tracks with outcomes: decompensation, variceal bleeding, survival all measured directly.

  • Non-invasive — no biopsy, no sedation
  • Quantitative — reproducible numbers, not impressions
  • Physiologic — staged H0–H5 on measured function

One scan, complete picture

Six indices. One complete snapshot.

PHM — Perfused Hepatic Mass

The core measure of functional reserve, and the strongest predictor of clinical outcomes.

fLV — Functional Liver Volume

Working liver volume, distinguishing functional tissue from total anatomic size.

fSV — Functional Spleen Volume

Splenic uptake and volume: a window on portal hypertension.

HAI — Hepatic Activity Index

Flags active alcoholic hepatitis and monitors recovery over time.

eFS — Estimated Fibrosis Stage

Fibrosis stage from measured physiology. No needle required.

eEV — Estimated Esophageal Varices

Identifies patients at risk of variceal bleeding before the first event.

The evidence

Validated where it matters: patient outcomes.

A publication record spanning two decades.

Anchored by an 8-year prospective multi-center NIH trial showing quantitative liver function predicts clinical outcomes. 

Browse all publications

HALT-C outcome trial

Quantitative liver function tests improve the prediction of clinical outcomes in chronic hepatitis C. Hepatology, 2012.

Function outperforms fibrosis

Physiologic staging predicts cirrhosis, decompensation and survival across etiologies.

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Bring quantitative liver diagnostics to your patients.

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