Technology

From a routine scan to actionable intel.

PROMEDX quantifies the standard nuclear liver–spleen scan, converting routine imaging into validated, reproducible measures of organ function.

Step 1

Scan

Patients receive a standard quantitative liver–spleen scan at a local imaging center. Non-invasive, widely available, reimbursable.

Step 2

Quantify

PROMEDX FDA approved software analyzes the study and computes the six functional indices with validated algorithms.

Step 3

Stage

Your physician receives a clear report: index values, trends over time, and a physiologic stage H0–H5.

Perfused hepatic mass

Functional reserve, imaged directly.

PHM measures the mass of working, perfused liver tissue. Patients with normal-range PHM can carry advanced fibrosis yet remain compensated: exactly why function, not scarring, drives prognosis.

  • Reproducible and operator-independent
  • Sensitive to change — ideal for longitudinal monitoring
  • Performance maintained in obesity and ascites, where elastography struggles

The signature model

Physiologic staging, H0–H5.

A staging system built on measured physiology — from normal function to decompensated disease.

H0Normal function
H1Early change
H2Mild impairment
H3Moderate impairment
H4Severe impairment
H5Decompensation risk

Stages reflect quantitative functional thresholds associated with clinical outcomes in the published evidence base.

Why quantitative

Where common tools fall short.

Blood-panel scores

Indirect and insensitive in key populations. Published comparative data show limited ability to identify patients at real risk.

Elastography

Measures stiffness, not function; published series report unreliable cirrhosis detection in important settings.

Biopsy

Invasive, sample-limited and impractical for monitoring — the reference standard nobody wants to repeat.

Comparative claims are supported by the references on the Publications page.